Displayed below are homes for sale in Mission Del Lago, a neighborhood in San Antonio, TX 78221. Mission Del Lago is located off US Hwy 281 near Mitchell Lake in Bexar County. Mission Del Lago is in the South Side Independent School District. Request more info or schedule a showing from the detail page of each of these Mission Del Lago real estate listings in Southside San Antonio. Receive email alerts whenever new Mission Del Lago homes hit the market!